Here goes: A Flow Cytometry Analysis specialist, a Manufacturing Manager, and a Validation Engineer walk into a bar and orders drinks and ask for a menu.
Bartender: Sorry only drinks today, no food. The chef was fired yesterday, finger got stuck inside the dishwasher. Embarrassing.
Flow Cytometry Analysis Specialist: (proudly) Simple diagnosis. The finger is blocking the water from reaching the water level sensor that activates release of detergent.
Manufacturing Manager: The key is to remove the finger. That will remove the blockage.
Validation Engineer: And turn the dishwasher off for a minute. That will reset the sensors.
Bartender: No, no, no. The chef was fired because the dishwasher was pissed and was threatening to sue the owner. You guys must work for that AF guy.
Validation Engineer: That's right, we are his biotech investment advisors. How did you know?