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Looks like we traded over 4 million shares in the last minute.
Bill
DrJan
Wonder if you've considered the credentials and background of our Chairperson Dr. Jiong Ma.
I sometimes wonder if she's disappeared but hope she's busy working on partnerships, submissions, etc. When we have our next ASM, would hope she'd be present to mingle with shareholders. She missed that opportunity earlier.
Bill
This was posted by rowdyboy45 on Stock Twits
[https://www.openpr.com/news/3473833/cognision-partners-with-anavex-for-phase-2-study-of-anavex-3-71
Saw reference to an interview by Mayo with Dr. Grimmer in earlier posts.
I recall the one at the below link from last year.
Not aware of any follow up interviews.
Talon and Wolf, in all fairness:
We seem to have more than our share of posts by those who don’t own Anavex continuously posting negative comments about the company and TGD.
To level the playing field, I’d respectfully ask some of our resident bashers to provide the names of companies in which they themselves do own shares.
I’ll spend all of my waking hours posting caca emojis to positive comments about their companies’ on their message boards.
Not much of a life I’ll admit but maybe I’ll figure out what joy they have in spending their time here.
Bill
George, don't be so quick to hit "submit".
"Then US President Ronald Reagan" is another way of saying "former US President Ronald Reagan".
Bill
During the early part of the call, I submitted the below question for the Q&A.
Was not acknowledged nor answered.
https://1drv.ms/i/s!Ah_Qw5dnDk02ykc1UyavybeJJG_f?e=DaA21m
Bill
Don’t know why you’re here . .
. . . nor where you came from . .
. . . nor why you persist in liking your own posts.
But, I know where you are headed.
Ladies and gentlemen, we have a new denizen in iggyland!
Bill
There you go, as promised.
Enjoy your sojourn in iggyland with Crescentmotor.
Bill
Tired of your snarky comments.
You add nothing to the discussion.
To ignore you go.
Now, as soon as I find a post from Investor, he/she will join you.
Bill
CTMFTB
Can the moderators fix this board?
Bill
George:
Did you even read the article you posted?
Maybe it's you that needs to brush up on reading comprehension.
This article completely misses the facts of this week's PR.
Could have come from an alternative universe.
And, by the way, you need to quit "liking" your own posts.
Bill
More denial from "Extremely Blowed up Ziggy".
Bill
Shorts getting blowed up "real good"!
I was a big fan of Secretariat.
Years ago on a precious metals blog, someone offered that Secretariat was a mare and opined that the greatest horse in history beat out her male counterparts decisively.
I responded that this might have come as quite a surprise to horse owners who paid millions in stud fees to Secretariat’s owners after he ended his racing career.
Bill
powerwalker
In looking at the $8.7 billion price tag paid for Cerevel, I’d bet a small sum that AbbVie previously approached Missling about AVXL and was turned away.
At the same time, comparing the prospects of AVXL and Cerevel, it looks to me as though we have seen a “floor” set for what an acquirer would pay for AVXL should they be successful in bidding.
My two cents, adjusted for inflation.
Bill
Tom:
I had cataract surgery on both eyes a few years ago. The process was painless and dramatically improved my vision after decades of having to wear glasses. You may want to compare the cost of multi-focal versus mono-focal lenses. I chose mono-focal which means I still need reading glasses when using a computer screen or reading expiration dates on food items.
The only negative side is having to keep up with the many eyedrops required before and after the surgeries. The aggravation is short-lived and worth the effort. The doctor will only perform the procedure on one eye at a time in the event the first procedure has complications. That’s just common sense.
On the plus side, I still think of the smokin’ hot ophthalmologist who performed the procedures.
Bill
Strategery (to borrow a word from Dubya).
Overall, many were not pleased with the call but it may be that there is a long-term plan in place for simultaneous approvals.
Given that the EMA process will take more time, it may make sense that approval is sought there first. Anavex can work first on that process, knowing that many of the documents used for EMA can also be used for FDA approval.
By managing both processes in tandem, getting EMA approval first will put additional pressure on FDA to expedite their review and approval. In such a case, simultaneous or near simultaneous approvals would have an even more positive impact on the share price.
Bill
Surprise, surprise!
Wonder how much Dave's lost since he was on this board in September pumping NWBO.
Not much time before the weather turns colder and he may wind up sleeping in his Yugo.
Bill
Expect AVXL to close GREEN today
With over one million shares traded.
Sorry, George.
Couldn't help myself.
Bill
More mindless drivel from the usual suspects.
Day in and day out until we get news.
I see that Rikker is still serving his apprenticeship with a laptop.
Thus far, he’s only learned to master using the mouse to pound the thumbs up key.
Up to now, any attempt to train him to use the keyboard has been unsuccessful.
Not sure we’ll ever see an actual post from Rikker but hope springs eternal.
Bill
Would it be considered "taunting" if we started a Go Fund Me page to pay for some emergency dental work for Adam?
Those Anavex guys are playing some real "smash mouth" football.
Bill
Nidan, very much appreciate your post.
Years ago, I was handed a large bank operations group suffering severe quality problems and told to fix it.
In looking at approaches, I discovered Dr. Demings’ book “Out of the Crisis”. Using his principles, I initiated a broad-reaching program of incentives geared to having each work group study its procedures and devise quality improvement processes. Each group owned their “product” and were challenged to improve against their prior performance month-to-month. To make a long story short, over a year or so, each work group achieved perfect or near perfect monthly results against their target quality ratios. They were, in turn, rewarded monetarily. This went on until I retired. Within months after the program was scrapped over monetary considerations, quality in each group started declining again.
I was able to remotely attend one or Dr. Demings' last seminars before he passed.
His book is available on Amazon, including Kindle, for those interested in improving quality in their organizations. Not sure this would help the FDA much but should be of benefit to Dr. Missling's staff in conducting their trials.
Bill
Yes, you get it.
We are borrowing money from China and others in order to pay the interest on our debt.
This is unsustainable.
Bill
This board has been rendered useless.
Never have so many posted so much about so little.
Would be nice if many of those posting here would take a holiday until about Feb-ish.
Bill
Hoskuld:
Thanks to you and the others who posted your impressions from the meeting.
I may have missed it but did not see any reference as to whether Dr. Ma or any of the other principal executives were present.
Would have thought this might be a good opportunity to formally introduce Dr. Ma to the shareholders.
Thanks in advance.
Bill
Xena:
Glad to see you post again.
Please drop by whenever you can.
Best of luck with your health issues.
Bill
Will Hugh be holding a press conference?
Or, simply publishing his findings in Lancet?
Bill
Nidan:
You and your family have my deepest sympathies for your loss.
May God comfort you and yours.
Bill
No, you are correct.
There's nothing normal about the way this stock trades.
Things to ponder
From the earlier press release, it’s almost obvious that Dr. Missling was instrumental in recruiting Dr. Ma as a Board member in 2021. With all of her background, I wonder if she ever dealt directly or indirectly with submitting NDA’s to the FDA on behalf of one of the healthcare-related companies she served with. In that case, she’d likely have had some exposure to Dr. Jun Kin. If nothing else, over their long careers, they must have crossed paths during seminars and other events at some point.
If so, that leads to the possibility that Dr. Ma may have been influential in the effort to recruit Dr. Kin to join Anavex. That’s connecting some dots that maybe aren’t there but not outside the realm of possibility.
My point is that, contrary to what some say about Dr. Missling, I see these moves as potentially being driven by his own long-term strategy for the company. First, looking ahead in hiring his eventual replacement as Board Chairperson, second, the timing of some the other hires leading up to Dr. Kin, and now announcing the next phase in corporate governance.
Hoping there is at least some credence to these thoughts.
Bill
I can think of one reason.
Anyone wonder why AVXL is still registered and incorporated in Nevada?
Anyone know of a real = non-grift firm that isn't incorporated in Delaware?
That's where corporations have the most protection
They don't want their corporate documents stored in a garage.
Bill
Welcome back, Mayo.
Look forward to your next release.
Looks like our friend Fitzy folded his tent right after you came back on the board.
Of course, if you look at his history, since he was first born in 2017, he’s only ever posted on two stocks (Anavex and Sorrento Therapeutics) and in over 1900 posts that I skimmed through, he never had a single positive post on either company. Then, before being “stuffed” this morning, he started in with negative comments on you.
Makes one wonder what his motivations are.
Bill
sab63090
I can vouch for the ultrasound method for removing kidney stones. Had one removed via the old approach years ago and it was not pleasant afterwards.
The ultrasound approach was not painful and recovery was easy.
JMHO
Bill
Seems like only yesterday that Dr. MacFarlane completed his presentation at CTAD and Dr. Missling hosted his conference call the following Monday.
Since then, we’ve been treated to no end of opinions regarding how the claimed test results could not be possible. We’ve had negative posts by eminent (in their own minds) statisticians, PhDs in Chemistry and Bioethics and at least two members in good standing of the Elbonian Medical Association.
We’ve made a lot of new friends who have only recently opened their iHub accounts to share their expertise and wisdom.
I’m certainly grateful for the altruism that has been bestowed on us longs. Regardless, I think I’ll continue holding until Anavex follows up with the data we still need.
Bill
Yep, Jager.
I noticed that also.
Brand new alias, born only today.
I'm sure we'll see more in the next few days.
Bill
My thoughts on the Missling question.
Previously, I’ve noted that Dr. Missling has a problem in communicating with understandable enunciation. Also, I’ve suggested he spend the time and money to correct the problem or else engage someone on the team or an outsider to make important presentations on his behalf.
But to suggest that he is not a suitable CEO to lead the company to revenue generation is frightening based on one of my previous experiences.
Years ago, I held stock in another biotech with a strong candidate that was ultimately approved. The CEO we had at the time was also highly-degreed but did not perform well in presentations. He did not have the “zing” some thought was needed to excite the medical and investor communities.
The controlling shareholder brought in an outsider to replace the CEO. The new CEO was touted as a superior marketing talent who would take our sales to extraordinary levels. He brought in members of his former marketing team at another company.
Seems that within six months we got reports that the marketing team was “stuffing the sales pipeline”, booking sales that were not actually accepted by the clients. Further investigation revealed that this same marketing team had been guilty of the same practice at their previous company.
Long story short, the stock tanked as there were investigations. I sold my shares at a considerable loss. The company was taken over by a competitor which is still enjoying sales of the former company’s products years later.
We’d probably still be a separate, profitable company had we held our course and retained the “dull-speaking” CEO who had brought us success in research and development.
For those who want Missling to be replaced, be careful what you wish for.
Bill
Thought the conference call went better than I expected. Would be even better if Missling would take a course in diction so he can be better understood.
Apparently some shorts will continue to bash regardless of what we all see.
About the only other thing Dr. Missling could have done to please some would have been to offer a download of a coupon for a free ice cream cone at Baskin Robbins.
Bill
Bought my first shares on August 4, 2015.
Added periodically since then (seemed to buy too many at or near the top at times before price fell again).
Be that as may be, I'm hoping to be vindicated in my holding for all these years.
Counting on this stock to provide generational wealth for my kids, grand-kids and that handsome new great-grandson who'll be 11 months old in December.
Good luck to all the longs on this message board.
Bill