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iwfal

03/09/12 11:12 PM

#138534 RE: exwannabe #138530

Agreed. But it still fits a common mindset.

"The trial was powered as we see fit, some data came in bad, but we maintain our view of the original power assumptions."




Agreed that that is the mindset - but it is an asinine one since I'd bet that >90% (original typo was <90%) of the time the HR for the post interim events is closer to the HR seen at the interim than it is to the HR guessed prior to the start of the trial.

Replacement post - since I had a sign error in original post