Replies to post #138534 on Biotech Values

[exwannabe]

OT Replacement post - since I had a sign error in original post

LOL, I caught that and thought about taking you up on your bet, but very carefully wording it so you ended up on the wrong side w/o knowing it.

I decided not to only because I make so many dumb typos that it is best I not worry about others' mistakes. :-)

[DewDiligence]

Why couldn’t (shouldn’t) a futility test be based on a linear combination of: i) the a posteriori power of the trial based on the actual data to date and the original powering assumption for the data yet to be reported; and ii) the a posteriori power of the trial based on the actual data to date and the assumption that the data yet to be reported are consistent with the data to date?