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Re: exwannabe post# 138530

Friday, 03/09/2012 11:12:13 PM

Friday, March 09, 2012 11:12:13 PM

Post# of 257443

Agreed. But it still fits a common mindset.

"The trial was powered as we see fit, some data came in bad, but we maintain our view of the original power assumptions."




Agreed that that is the mindset - but it is an asinine one since I'd bet that >90% (original typo was <90%) of the time the HR for the post interim events is closer to the HR seen at the interim than it is to the HR guessed prior to the start of the trial.

Replacement post - since I had a sign error in original post

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