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hoffmann6383

08/26/22 1:31 PM

#508356 RE: DL7 #508353

Where did he say that? I'm not sure where he is getting that information from, but from the slides in the presentation and all the data I've seen we are at about 5% survival after 5 years going with the SoC.

Also, I'm sorry to hear about your mother and also glad that you had that additional 9 years with her :)
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flipper44

08/26/22 1:34 PM

#508359 RE: DL7 #508353

What trial was your mom in?
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exwannabe

08/26/22 1:43 PM

#508361 RE: DL7 #508353

Dr. Musella is saying that 0% survived in the external control arms for 5 years. However the presented TLD from May 10th reported a 5 year survival of 5.7%or 5.8% in the external control arms. This is a very substantial difference and I am not sure I understand


The reason is that the trial data they compared to had almost no patient data reported for the full 5 years. About 20 is all.

Most GBM trials do not follow that long because for practical purposes the outcome is known by 3 years or so.

Of the 20 or so who were reported on at 5 years, none were alive. That is as opposed to the expected 1 being alive.
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marzan

08/26/22 8:44 PM

#508464 RE: DL7 #508353

good son, took care of your gbm mom very well; thanks DcVaxL for giving your mom a 9 yr amazing survival; precious time indeed!
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Hopeforthefuture3

08/27/22 9:57 AM

#508510 RE: DL7 #508353

DL7, thank you for sharing the story of your mother, very sorry for your loss.
My thanks to your late mother and entire family for participating in this trial to help find improved treatments for this awful disease.
If I may ask how was her quality of life before recurrence and did they have any additional treatment(s) after recurrence? Just hoping to better understand real world examples from the point of view of the patient
Thanks and best wishes