I was thinking the issue with not using a SOC chemo/radiation treatment was that there is a 8 day mfg period after tumor resection plus a 30 day quality control testing before making it available to the patient, therefore the tumor had ample time to regrow. The question then is whether DCVAX-L without chemo/radiation follow-up would be sufficient to deal with a full grown healthy tumor.
Also the purpose of the chemo/radiation was not so the dendritic cells could pick up more tumor antigens, not needed because it already has done that during the mfg lysate process. The purpose was to weaken the tumor so the DCVAX-L empowered DC's would reach its target.
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