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Re: Hoskuld post# 474883

Sunday, 11/24/2024 4:58:19 PM

Sunday, November 24, 2024 4:58:19 PM

Post# of 515548
Wasn't aware of your private conversation. IR's "not sure" comment to you was silly and of no value. Trials are inherently unsure, such a comment is hindsight justification, and the company repeatedly asserted the Rett trial was "potentially pivotal". Keep the latter particularly in mind.

The EMA clearly does not require two Phase 3's. Our Rett and AD trial designs were suboptimal under the circumstances, to be sure, as we are not resource constrained. The company states and demonstrates a lot of confidence and optimism.
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