NorthWest Biotherapeutics Inc (NWBO)

[MI Dendream]

I am one of the originators of this thesis. In my thesis, neither investigators, patients nor company knew that placebo was removed. BTW this was my thesis in August of 2015 which I shared with everyone invested as a connection with me.

Evidence to this thesis is the FACT that the final 31-32 patients were only placed on treatment, no randomization to placebo. While this only directly ties to those not yet randomized, the rationale to do this creates a moral and ethical obligation to treat every human being who volunteered their life to the study of a potential therapy. There is an obligation to those patients to first do no harm and to progress with GBM is to die, at least if they stay on placebo, and at that point it is not known whether or not DCVax can rescue a portion of them after progressing, it was only known that it delays death before progression.