Replies to post #439302 on NorthWest Biotherapeutics Inc (NWBO)

[survivor1x]

Didnt information around method B come out sometime after the halt. I know method b is direct. But hear me out, this is a platform technology. What if during the open label direct trial they learned things about manufacturing that would also be pertinent with L. Cell signaling within the batch that would make it more potent?

[Reefrad]

Can you point us to evidence of this fact? It’s thrown around quite a bit but I would love to see the actual evidence of it.

Thanks

[sentiment_stocks]

Evidence to this thesis is the FACT that the final 31-32 patients were only placed on treatment, no randomization to placebo.

This is NOT a fact.

The fact that there are lesser control patients than originally intended could have been spread out over the length of this ten year trial. I can assure you that the company has doubled, tripled and quadrupled down on the premise that the randomization was carried out over the entire length of the trial.

This path, IMO, is a rabbit hole with only General Woundwort waiting on the other side.

[ae kusterer]

'MI Dendream:In which post of yours have you articulated this thesis in the most comprehensive way?


MI Dendream Thursday, 01/27/22 10:09:53 PM
Re: sentiment_stocks post# 439298 0
Post #
439302
of 439348
I am one of the originators of this thesis. In my thesis, neither investigators, patients nor company knew that placebo was removed. BTW this was my thesis in August of 2015 which I shared with everyone invested as a connection with me.

Evidence to this thesis is the FACT that the final 31-32 patients were only placed on treatment, no randomization to placebo. While this only directly ties to those not yet randomized, the rationale to do this creates a moral and ethical obligation to treat every human being who volunteered their life to the study of a potential therapy. There is an obligation to those patients to first do no harm and to progress with GBM is to die, at least if they stay on placebo, and at that point it is not known whether or not DCVax can rescue a portion of them after progressing, it was only known that it delays death before progression.