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Compiled: SLEEP 08/08/19

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Anavex Life Sciences Issued New U.S. Patent for ANAVEX®2-73 Treatment of Neurodevelopmental Disorders including Rett Syndrom... GlobeNewswire Inc. - 1/8/2020 7:00:10 AM
Anavex Life Sciences Reports Fiscal Year 2019 Financial Results And Provides Clinical Study Updates GlobeNewswire Inc. - 12/16/2019 7:00:10 AM
Anavex Life Sciences to Announce Fiscal 2019 Year End Financial Results on Monday December 16, 2019 GlobeNewswire Inc. - 12/10/2019 7:00:10 AM
Citation Growth Corp. (OTCQX: CGOTF) Weathering the Cannabis Downturn InvestorsHub NewsWire - 12/9/2019 7:23:11 AM
Anavex Life Sciences Presents ANAVEX®2-73 (blarcamesine) Data at 12th Clinical Trials on Alzheimer's Disease (CTAD) 2019 Con... GlobeNewswire Inc. - 12/4/2019 7:00:10 AM
Anavex Life Sciences Receives Rare Pediatric Disease Designation from FDA for ANAVEX®2-73 (blarcamesine) for the Treatment o... GlobeNewswire Inc. - 11/14/2019 7:00:00 AM
Anavex Life Sciences Announces Publication of Foundational Data for ANAVEX®2-73 (blarcamesine) in Rett Syndrome GlobeNewswire Inc. - 11/6/2019 7:00:00 AM
Anavex Life Sciences Announces ATTENTION-AD ANAVEX®2-73 Extension Clinical Study in Early Alzheimer’s Disease GlobeNewswire Inc. - 10/9/2019 7:00:00 AM
Anavex Life Sciences Issued New U.S. Patent for Composition of Matter Covering ANAVEX®2-73 for the Treatment of Alzheimer’... GlobeNewswire Inc. - 10/2/2019 7:00:00 AM
Anavex Life Sciences Presented at the 6th Annual European Rett Syndrome Conference Preliminary Clinical Efficacy Data from th... GlobeNewswire Inc. - 9/27/2019 3:00:00 AM
Anavex Life Sciences to Present at the 2019 Cantor Fitzgerald Global Healthcare Conference GlobeNewswire Inc. - 9/26/2019 7:00:00 AM
Notice of Effectiveness (effect) Edgar (US Regulatory) - 9/23/2019 6:35:19 AM
Anavex Life Sciences to Present at the Ladenburg Thalmann 2019 Healthcare Conference GlobeNewswire Inc. - 9/18/2019 7:00:00 AM
Post-effective Amendment to Registration Statement (pos Am) Edgar (US Regulatory) - 9/17/2019 5:16:10 PM
CLS Holdings (CLSH) $1.15 Price Target - MASS Approval for Recreational License InvestorsHub NewsWire - 9/17/2019 7:17:00 AM
Withdrawal of Registration Statement (ammendment) (aw) Edgar (US Regulatory) - 9/16/2019 4:17:42 PM
Anavex Life Sciences Announces Preliminary Clinical Efficacy Data of its U.S. Phase 2 Clinical Trial of ANAVEX®2-73 in Patie... GlobeNewswire Inc. - 9/16/2019 7:00:00 AM
Current Report Filing (8-k) Edgar (US Regulatory) - 9/13/2019 5:11:08 PM
Prospectus Filed Pursuant to Rule 424(b)(5) (424b5) Edgar (US Regulatory) - 9/13/2019 5:07:24 PM
Securities Registration Statement (simplified Form) (s-3/a) Edgar (US Regulatory) - 9/13/2019 5:02:44 PM
Anavex Life Sciences to Present at the Janney Healthcare Conference 2019 GlobeNewswire Inc. - 9/5/2019 7:00:00 AM
Anavex Life Sciences Announces Initiation of the EXCELLENCE ANAVEX®2-73-RS-003 Clinical Study in Pediatric Patients with Ret... GlobeNewswire Inc. - 9/4/2019 7:00:00 AM
Quarterly Report (10-q) Edgar (US Regulatory) - 8/7/2019 4:07:28 PM
Anavex Life Sciences Reports Fiscal 2019 Third Quarter Financial Results And Provides Clinical Study Updates GlobeNewswire Inc. - 8/7/2019 7:00:00 AM
Anavex Life Sciences to Announce Fiscal 2019 Third Quarter Financial Results on Wednesday, August 7th, 2019 GlobeNewswire Inc. - 8/2/2019 7:00:00 AM
XenaLives Member Level  Thursday, 08/08/19 06:21:44 AM
Re: None
Post # of 232108 
Compiled: SLEEP 08/08/19
(see also insomnia patent under IP)

Sleep in the Deep Dark

One Night of Sleep Fights Alzheimer's

Sleep deprivation accelerates Alzheimer’s brain damage
Study in mice, people explains why poor sleep linked to Alzheimer’s
by Tamara Bhandari•January 24, 2019 (from georgejjl)

Sleep history predicts late-life Alzheimer's pathology 17-JUN-2019 (from raja48185 )

Dollars to donuts..>8 patients in P2a had sleep issues.

Cortical thinning in patients with REM sleep behavior disorder is associated with clinical progression.
Two members of AVXL SAB involved (from kevli33)

Circadian Clock Plays a Role in Health, Peak Performance (from Kevli33)

Chronic disease and Sleep:

The bar goes lower still for our ace in the hole. (from baltimorebullet)

Article on the importance of sleep as we age:

Australian study on Improving Sleep to Prevent Alzheimer's Disease

Aging induced endoplasmic reticulum stress alters sleep and sleep homeostasis. https://investorshub.advfn.com/boards/read_msg.aspx?message_id=148334968
(see also subsequent posts by georgejjl on the same subject)

Good general discussion of the neurological aspects of sleep (from Xena :), not an endorsement of the products advertised:

Sleep Disorders in CNS Diseases

Sleep and aging, two sides of one coin (from biostockclub)

More on AD and sleep...as predicted... (from nidan7500)

More on Parkinson's and sleep (from nidan7500):

Sleep is a pervasive issue:

A real life anecdote about sleep and Parkinson's (from cinic)
Podcasts at the bottom of the page.

A new way to monitor sleep - cardiopulmonary coupling. (from roygbiv)

Alzheimer's specific sleep scale:

How sleep fights infection, (from MycroftHolmes)

Sleep restoration likely a component of MOA and the positive effect of 2-73 across multiple CNS diseases:

Restoration of normal sleep patterns could be key to checking the advance of plaque formation in prodormal Alzheimer's.

Might Anavex-facilitated Sleep Prevent Alzheimer’s? (from Falconer66a)

Alzheimer's and Sleep:

Sleep in Parkinson's disease -

Deep Sleep and early signs of Alzheimer's

Falconer posts a major paper on sleep and Alzheimer's :

Autism and sleep...

In Peace, In War
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