Makary resigns from FDA post. Source: CNBC- TV announcement.

CNBC-TV: Makary resigns from FDA.

Makary resigns from FDA. Source: CNBC-TV.

Bought 7000@$0.51, 11/4/2012; 5000@$0.56, 1/25/2013 in taxable account; 5000@$0.53, 4/26/2016 in IRA. Best has been NVDA: bought 7600 split-adjusted shares @$0.43, 12/24/2009, trading near an all-time high today. GILD, IBM, SBUX shares date from purchases in 1990s

Dew, would appreciate an explanation of how you calculated a 21% buyout premium for CPRX today.

Another Italian company, Angelina Pharma, wants to enter the United States pharmaceutical market. Today Angelina bought U.S. based CPRX for $ 4.1 Billion, or $31.5/share. We have 17K shares of CPRX, bought at $0.52/share. Catalyst has 2-3 FDA- approved products in rare disease market. Does Recordati have similar plans with Amarin current partnership?

Catalyst Pharmaceuticals (CPRX) is acquired by Italian Angelina Pharma for $31.5/share, a ~ $4.1 Billion deal. Rare brain, neurological Indications. We have 17,000 shares.

Eleven, nobody has noticed that seair  has reported for Amarin that smaller kg quantities of IPE are imported/landed into Charleston. Larger kg quantities of IPE are landed into Savannah. I assume Amarin must have a reason for this. Do we know this time whether the journey from the Netherlands to the 2 U.S ports was by air-freight or by sea? Does BASF ship any omega-3 to that Netherlands supplier, or to Basel/NVS in Switzerland via the Rhein? Is the Netherlands supplier new or old to Amarin?
Thanks for the very  useful information regarding the Hikma supplier identity and their shipments into Tampa.
Is EPIC related to or controlled by Dr. Reddy? Do we know whether the Chinese supplier used air-freight or sea containers, all kept at proper temperature, landing in the Newark area?

“affirmed”, not “reversed”, your last paragraph. Further, S. Court is reviewing judgment of CAFC, not that of District Court. Your hypothetical opinion of Supreme Court fails to even mention CAFC except in that last paragraph.

Reuters reports today a decision of CAFC rendered last year. (? Why today?). As I said, best check Reuters for accuracy.. I saw the Reuters report on Schwab news feed, read too fast, I was not accurate either. 

Reuters, 2:58pm: Amarin wins in S.Ct. Better check that for accuracy.

Look at NEJM, April 30, p. 1669. “Substandard Generic Drugs—-Threats to Patient Safety and National Security “. This board talked about generic IPE drugs manufactured in the Middle East(Israel, Turkey?), 23k bottles of 120 capsules each melting, “exploding”, likely due to premature oxidation. The authors, like me a few weeks ago, suggest an embargo against importation of such unsafe drugs. Then look again at the S. Ct. Trump tariff decision a few weeks ago, LRI v. Trump, 607 U.S.___(2026) at page 14-16. More later.

I disagree with you, BBI. Hikma lawyer had/having a tougher time at oral argument.

Wrong court, lizzy. You name CAFC judges, not S.Ct justices.

Volume has increased, zip. Near 250k shares traded at 2 pm

At 1:55 pm, today seems to be an exception……remember the Fed decision is today at 2 pm

We made a 3-night round-trip to Princeton last Tuesday-Friday to see new art museum and new engineering buildings. The campus is greatly enlarged; lots of Asian students(~40%) in the Graduate College. Saw both BMY and AZN plant facilities north of Trenton. We took I-95 out of D.C beltway to I-295 that connected to Nassau Street. I think we saw SUN and PFE facilities along the way also; don’t remember if we saw ANIP HQ this time(wife drove AUDI-S4, I slept part-time). JNJ has facilities in New Brunswick, short drive northeast of Princeton. 

We are driving to Princeton next week to see friends, a new art museum, and to learn from graduate students how they are using AI and quantum computing to identify/improve new biological compounds that could be useful in pharmaceutical industry. Another alumnus (founder of Costar while still an undergrad student) just made a sizable donation to fund the new department. I left Princeton in 1961 with an M.S. Chem Engg for law school in Washington D.C. Our time there will not conflict with the dates you mention.

Can anyone identify who dumped a relatively large number of AMRN shares at ~ 11:10–11:20 am this morning? See candlestick chart.

We received one proxy in joint account last week(Schwab), none in my IRA. 

Methinks Amarin may now be competing with generic prices via an authorized generic. Can you tell us what state you reside in?

Open the bottle. What Trademark is printed on the capsules?

Representative Issa(R-California) chaired a House Judiciary subcommittee-Committee “Oversight” meeting at 10 am this morning where Mr. Squires, Under Secretary of Commerce and Director of the PTO, was the one invited witness. Among many topics discussed, the backlog of 800k + patent applications is being reduced and Examiners are using AI to shorten the many hours normally spent in searching/reviewing prior art to minutes. The link to that 2 hour meeting is archived; original YouTube link was provided by PowerSweep on the NLST IHub board

I see $1.76 on greater volume at 11:15 am Schwab 

Agree with treble damages possibility. Bought additional 1100 shares AMRN this morning.

When I saw Amarin trade some shares at $17, I began thinking someone read and acted on that speculative message. That embargo could actually be made to happen before the Supreme Court hearing date in late April…….maybe worth sending some documents (akin to those timely sent to Solicitor General Sauer) to the WH, the Vice President, and HHS, Treasury and Commerce cabinet members. Links to EPA Drug Initiative II v. Hikma et al Petition for a Writ of Certiorari are readily available for details of the collaborative fraud, unfair competition and inequitable conduct; remember Carter’s embargo against certain specific steel products? 
Congressional Oversight Committees continue to be busy with certain pharmaceutical industry compounded composition warnings re safety, costs and public health concerns. What entities controlled or actually manufactured those ~ 23000 bottles of generic IPE that were recently recalled?

Ireland’s Prime Minister, Micheal Martin, is planning to visit the WH on St.Patrick’s Day this year. According to WSJ today( page A3), Ireland is planning to invest $6.1 billion dollars to support various U.S. companies like “AMZN and other U.S. data center operators”. “ High tech construction [is] Ireland’s largest export sector outside food.”

I am imagining a WH conversation like this, from Martin: “We plan a [something like ~ $100-200 million] investment in shares of Ireland-based Amarin. Its current drug, Vascepa, is produced in the United States and elsewhere.”
From Trump: “That’s great. We will place an embargo on all specific generic IPE labeled products imported into the United States. Members of my cabinet have told me about the egregious fraud two of those generics committed in our Federal Courts and in negotiations with FDA leading to their IPE labels. I’ve read the Ten Commandments. Generics coveted the CVD market of Amarin, they lied and attempted to steal that market and are unfairly competing with Amarin and Vascepa. That remedial embargo should help your Amarin investment increase in value. Did you bring a bowl of shamrocks?”

OT: Bought 300 ORCU ETF yesterday with available cash. PT ORCL= $300, KeyBank

No mention of any generation

Where is everybody? This is post #5 today. OT: sold 300 ORCL today on reports its NVDA Blackwell  data chips will be outdated before the distribution centers using them will be operational in December because NVDA’s 100x more powerful Vera Rubin chips will be shipping in volume in December.

Thank you for that information. I have been prescribed/taking Vascepa every day since 2013. I will be 89 in April 2026.

Se gfp2437z post yesterday, 3/03/2026, for copy/paste article from IHub Biotech Ideas board about unexplained deaths during sleep. Covid and other viral infections research with brain imaging provides a clue to causation; reported by 2 research scientists from NIH and San Francisco.  Looks very pertinent here, IMO.

I should have given credit to founder/moderator gfp927z on rarely visited (840 + posts since 2020?) IHub Biotech Ideas board for the link and a copy/paste of entire article yesterday, 2/3/2026. No sign-in required there.

https://www.asrn.org/journal-advanced-practice-nursing/3449-how-covid-quietly-rewires-the-brain.html

Everyone should read this link. My brother died earlier this year, a sudden unexplained death— he simply died while asleep.

I agree. 

CaptBeer’s charts re “Fenofibrate switchover” tell  a more encouraging story. Btw, what can you tell us about government embargo’s against specific products under U.S. trade laws after last Friday’s Supreme Court (170 pages total read) decision on tariffs/taxes/duties? Might 1)public safety + 2)fraud in obtaining a generic label in the process of FDA label negotiations be factors favoring an embargo against a pair of generics here? Trump placed/delegated V.P. Pence to be in charge of Medicare fraud about an hour into his State of Union address. The Secretary of Commerce is still in Office. An embargo against a specific product under U.S. trade laws prevents importation of that product.

We still hold shares of both EYPT and OCUL. My wife’s (and my)eye doctor, a retina specialist, is an investigator in the EYPT clinical trial(s). He is aware of what both companies are doing in this sector/space. We currently have no plans to sell our shares held in either company. Keep your eye on LITE, moving data at speed of light in numerous technology sectors

What is new there?

I expect further news of collaborations in late March from New Orleans—-NVS will be there also, I think.