John, ""I don't think, hypothetically, that bavi's "proposed MOA/approach"* is behind the times. ""
Well that places you in a minority regarding anti-cancer MAbs for the most part. Yes one might make some exceptions for those few MAbs which directly modulate T-cell. That sure as hell isn't what Bavi is thought to do.
"very legitimate and validated approaches of checkpoint inhibition"
Just what does checkpoints and their inhibition have to do with Bavi? Drugs which damage DNA or alter microtubule dynamics exert their anti-cancer effects in a large part by taking advantage of defective checkpoints that may be found in tumorigenic cells in many cases. Since when is Bavi involved in abrogating checkpoints?
Market Data 
Markets 
AI
