I can't think of any overarching way to "regulate greed". But you can certainly do some seemingly very simple things to take away the playground, or at least make it less fun to be there.
Simple things like:
- provide audited financials, if you can't, you don't deserve to be public.
- your TA must be fully transparent and publish all share structure numbers at regular intervals. if not, they should not be allowed to act as a TA. if there is cost to the company, they must bear it, or not trade.
- the real insiders should not be hidden need to be bound by ALL regs. away with this nominee nonsense.
- lawyers who work in OTC water should be highly scrutinized by their peers. perhaps a dedicated board with the ability to strongly recommend disbarment for offenders.
- stiff fines and jail time for those who orchestrate these scams. enough with the wrist slapping, especially for recidivists.
Just a few ideas ;-)
I'm sure there are others here with far more knowledge of the inner workings of the OTC who could think of better ways to deal with the mess. But these might be a good start.