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Re: iwfal post# 138534

Monday, 03/12/2012 5:40:20 PM

Monday, March 12, 2012 5:40:20 PM

Post# of 257443
Why couldn’t (shouldn’t) a futility test be based on a linear combination of: i) the a posteriori power of the trial based on the actual data to date and the original powering assumption for the data yet to be reported; and ii) the a posteriori power of the trial based on the actual data to date and the assumption that the data yet to be reported are consistent with the data to date?

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