Replies to post #131159 on Biotech Values

[mcbio]

Well MDV3100 in early stage trials (at a higher dose) had a couple of seizures reported as SAEs.

Do you know how much higher that dose was that caused the seizures than what was used in Phase 3? Just curious if we are talking something on the order of double or more or if it's a much narrower difference in dose.

[jq1234]

Note the steroid dose for Zytiga is pretty small, but I think it is enough to make doctors think twice if they have a comparable steroid-free alternative.

I don't think it will make big difference in the last line patient population. It certainly will make difference in earlier stages of PC.