While the published short position has floated around 50 million (with almost 1.6 billion shares in the float), the daily volume is around 2 million on average. That's 25 times larger than the reported short position, and can lead to a rapid liquidation of that short position on a good rise in the share price when the share price actually does something. That too, is a fact.
Another interesting fact is that on average, most stocks trade between 1 (16m) to 3% (48m) of their total float (about 1.6 in NWBO's case), and yet NWBO trades at about .00125% of their float. That means the retail holders of this stock are holding firmly onto their positions. That type of stubborn conviction won't serve the shorts too well in the event of an appreciable rise in the share price.