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rx7171

11/15/25 10:53 AM

#508338 RE: Hosai #508325

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abew4me

11/15/25 11:29 AM

#508345 RE: Hosai #508325

Let's hope that they are making this Blarcamesine vs. Mabs comparison...and not just giving them positive statistics of Blarcamesine by itself.
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gerry57

11/15/25 4:31 PM

#508402 RE: Hosai #508325

Thank you, by far the most informative post I have read . I have been reading abstracts for hours trying to articulate why gwas exponential number as being suggestive is flawed because of an intuitive sense I couldn’t explain. In my reading I also suspect that having a variant of both sigma1 and the col24a1 simultaneously would be more harmful and affect homeostasis ,autophagy and neuronal metabolism in a more egregious way. In short the gene pool we are concerned about is far smaller than what gwas considers. There are at least 28 col genes and 3 in particular are more pronounced in neuronal function col24a1, col25a1 and col6a1 . Though it is too late in the game I do hope the regulators consider these aspects more than chance data occurance.