Replies to post #503494 on Anavex Life Sciences Corp (AVXL)

[boi568]

I don't think Jesse is suggesting a second Phase 3 trial as the condition.

[attilathehunt]

Wouldn't a CMA pose a recruitment problem if a confirmatory trial is required? Why would anyone risk a 1 in 3 chance of being in the placebo arm

I don't think a confirmatory trial would have a placebo arm.

[Investor2014]

A confirmatory RCT trial may be required as so far Anavex haven't run any as would be the norm. The outcome of the P2b/3 ended up looking more like a P2 trial than a P3 pass to protocol on all endpoints met with flying colours.

If a P3 RCT Confirmatory trial is a condition under CMA, then there are plenty countries to run the trial in where blarcamesine is not approved or marketed.