You clearly have no idea what you’re talking about if this is your position. This happens not infrequently. I did the research a few years ago. Not sure I can find it quuckly but you do see a variety of drugs that are well known where they did not do well initially, and even got approved on other criteria, including your favorite, I believe, Optune, which failed its initial trial and did not have a true placebo. Now that does not mean you won’t come up with further excuses for your preferences and why you must be here all day every day undermining views of DCVax-L, but that is the reality.