Replies to post #760788 on NorthWest Biotherapeutics Inc (NWBO)

[exwannabe]

Another point: Another poster, may have been Flipper, pointed out that in that thread AF is referring to document that doesn't exist. So, is he revealing a knowledge of DMC proceedings that he should not have or still playing up the false story of the DMC having issued a stop for futility? As those of us who were here know, that story became so prominent that the head of the DMC was forced to issue a denial that such a thing had happened. Of course there are those who believe that the DMC denial was a fake. So, by bringing it up, is AF indicating that he is privy to documents he should not have? And did he mess up by bringing it up as it is not germane to the case?

You are conflating 2 different DMC issues.

Per NWBO there was supposed to be an efficacy IA in early 2014 that could lead to an early halt for efficacy. Then radio silence. So AF called BS. Turned out that NWBO was hiding something, but it was not a futility finding in 2014 as that was called off. They hid the fact that they needed to run the trial longer as they did not expect it to be effective as previously assumed.

The 2015 IA for efficacy did happen as NWBO said it would. They were charged with providing a recommendation to continue, halt for futility, or call the trial an early success. But NWBO again went into radio silence on what happened. despite having hyped the possible early success.

I have no idea what documents you are talking about. AF never posted anything that was not based on the simple fact that NWBO went dark when they should have been able to report good or bad news.

Though I cannot prove it, is obvious to an anybody in the space that in 2015 the DMC reported that the trial was unable to establish the primary endpoint of PFS, thus formally could no longer enroll patients signing a consent that asserted the purpose of the trial was to do so. So the FDA issued the hold. LP tried to get the endpoint changed to OS at that time (which was why she said they hoped to restart screening soon). But the FDA did not allow it.

A total shitstorm of crap from LP on this. You guys deserve every penny or your losses.

What is worse, if -L actually does work it is not progressing to the market because LP prefers to build CDMO's for herself than run the needed trials. F'ing sick.

[ccie1024]

is AF indicating that he is privy to documents

Or is he merely propagating a rumor, a rumor that can be traced to a source? Which may be even more valuable information?