Replies to post #748772 on NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

I noticed the same, but as in all speculation, we’ll have to wait to see if it involves DCVax.

[FeMike]

I bet it is the Win-Glo programme.

Looks like it may involve DCVax-L, amongst other candidates. This looks like it may be one of the collaborations NWBO was talking about in the last Q.

(edited: took out the 'likely' and 'definitely' as this is certainly speculation and nothing "definite" about it - but I think it's a solid guess)

The Win-Glio Programme of clinical trials improves the effectiveness of cancer drugs by using them alongside drugs that modulate the immune system.

Both types of drugs have already been licensed or are in clinical development.

It’s known how these drugs work. It’s known what they do to tumours, what the correct dose is, and the potential side-effects. This isn’t starting from scratch.

Immunotherapy has already been successfully used with melanoma (skin cancer) patients. Because melanoma shares similarities to glioblastoma brain cancer there is every chance these successes can be replicated.

The Win-Glio programme, launched at the end of 2023, is developing its first trial for early 2025. It will involve ten patients who are due to have surgery for glioblastoma. These patients will receive immunotherapy drugs to target the glioblastoma cancer. There will be multiple trials, each using different immunotherapy drugs. A significant response rate in one of the cohorts of patients will allow further patients to be enrolled into this group to give a statistically significant number of patients for further analysis.

The Win-Glio Programme is led by Dr Paul Mulholland. Paul is a medical oncologist who exclusively treats brain cancer. He is a consultant at University College Hospital, the National Hospital for Neurology and Neurosurgery (part of UCLH).

[attilathehunt]

I am excited to announce to the house that we will be opening a drug trial for glioblastoma brain tumors in May".

Doesn't sound good to me....If DCVax is working (and SHOUD be approved by May) why be excited about another trial if one is already approved and working?


Something fishy....May go in hand with the recent uptick in dilution....Need another trial?


Lets just hear from the MHRA...enough already...415 days since submission...It's time for a decision.

[evanstony]

children next...

[dennisdave]

"I am excited to announce to the house that we will be opening a drug trial for glioblastoma brain tumors in May"

I think this refers to the combo trials NWBO is planning as described in the last 10Q

[Lykiri]

Besides Siobhain McDonagh MP, another member of the House of Commons has been personally affected by glioblastoma, as her brother-in-law has been diagnosed with this devastating disease.

Monica Harding is the Liberal Democrat MP for Esher and Walton, and has been an MP continually since 4 July 2024.

Feb.4, 2025

Monica Harding MP
@monicabeharding
On #WorldCancerDay, I’m proud to be backing a much-needed Rare Cancer Law presented by
@DrScottArthurMP


A rare cancer is one that affects fewer than 6 in 100,000 people. They are often the most complex and deadliest types of cancer and the most difficult to treat—partly because clinical trials are so limited.

Sadly, cancer touches all families and mine is no exception. My wonderful brother-in-law, Group Captain Pip Harding, was diagnosed at age 52 with a rare and devastating brain tumour—Glioblastoma. He was fortunate to find a pioneering brain cancer specialist, Dr. Paul Mulholland, who has been administering a promising treatment known as oncothermia.

But oncothermia, like many groundbreaking treatments, is not available on the NHS and Pip’s treatment has been entirely funded by friends and family on a go fund me campaign.

The Rare Cancer Bill would encourage pharmaceutical companies to invest more in researching these underfunded cancers, giving hope to those facing these devastating diagnoses.

If we want to save lives, we must commit properly to NHS funding and incentivise companies to develop cutting-edge treatments. On World Cancer Day, let’s make that commitment— so that everyone affected by this terrible disease has a fighting chance.

On #WorldCancerDay, I’m proud to be backing a much-needed Rare Cancer Law presented by @DrScottArthurMP

A rare cancer is one that affects fewer than 6 in 100,000 people. They are often the most complex and deadliest types of cancer and the most difficult to treat—partly because… pic.twitter.com/MS0goX4Hwr

— Monica Harding MP (@monicabeharding) February 4, 2025