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Replies to post #40695 on SiNtx Technologies Inc (SINT)
The latest generation of ceramic bearing materials such as silicon nitride (Si3N4) [20], as well as a number of surface engineered coatings have been explored as potential alternatives to UHMWPE and metal articulations [21], [22], [23], [24], [25].
Silicon nitride particles are found to slowly dissolve in aqueous fluids [26] and the wear debris released from silicon nitride articulating surfaces are predicted to slowly dissolve in biological fluids [24]. Current methods are not designed to isolate and recover wear debris in such situations.
A volume of 0.018 mm3 of clinically relevant CoCrMo, Ti-6Al-4V or Si3N4 particles was injected into rat stifle joints for seven days of in vivo exposure
Mr Bond, they have a saying in Chicago: 'Once is happenstance. Twice is coincidence. The third time it's enemy action'.
One is an incident, two is a coincidence, three's a pattern, and four is enough for a warrant
examples of their medical applications that relate to spinal, orthopedic and dental implants, bone grafts and scaffolds, platforms for intelligent synthetic neural circuits, antibacterial and antiviral particles and coatings, optical biosensors, and nano-photonic waveguides for sophisticated medical diagnostic devices are all covered in the research reviewed herein. The examples provided convincingly show that silicon nitride is destined to become a leader to replace titanium and other entrenched biomaterials in many fields of medicine.
Silicon nitride, silicon carbide and diamond-like carbon as non-oxide ceramics are considered to be the new generation of materials used in hip prosthetics, particularly in the manufacture of acetabular cups, due to their excellent biocompatibility, osteointegration, and tribological and mechanical properties, but all three materials need more study. However, silicon nitride is the nearest to commercialization, through businesses such as Amedica Corp. and SyntX Technologies
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