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Re: boston745 post# 40695

Tuesday, 03/26/2024 10:59:35 AM

Tuesday, March 26, 2024 10:59:35 AM

Post# of 40972
Theres the new prospectus filed.

2016-2017, the CEO of Sintx and CEO of Zimmer were on the board of trustees of the OREF as i indicated in my previous post. Then in December 2018 Zimmer Biomet hired Dr. Saraubh Lal PHD. What this again shows is continued interest of Zimmer Biomet in Si3N4 for use as a material for medical implants that goes all the way back to 2003 when it acquired Centerpulse 21 years ago.

Before his hire Dr Lal published several studies pertaining to one particular material.

1. Biological Impact of Silicon Nitride for Orthopaedic Applications: Role of Particle Size, Surface Composition and Donor Variation

2. A novel method for isolation and recovery of ceramic nanoparticles and metal wear debris from serum lubricants at ultra-low wear rates

The latest generation of ceramic bearing materials such as silicon nitride (Si3N4) [20], as well as a number of surface engineered coatings have been explored as potential alternatives to UHMWPE and metal articulations [21], [22], [23], [24], [25].

Silicon nitride particles are found to slowly dissolve in aqueous fluids [26] and the wear debris released from silicon nitride articulating surfaces are predicted to slowly dissolve in biological fluids [24]. Current methods are not designed to isolate and recover wear debris in such situations.



3. Recovery of low volumes of wear debris from rat stifle joint tissues using a novel particle isolation method

A volume of 0.018 mm3 of clinically relevant CoCrMo, Ti-6Al-4V or Si3N4 particles was injected into rat stifle joints for seven days of in vivo exposure



4. Size- and Dose-Dependent Reduction of Oxidative Stress in L929 Fibroblasts by Silicon Nitride Particles Bone & Joint

You can find these and other studies on Dr. Lal's research study page:
https://www.researchgate.net/profile/Saurabh-Lal

Sintx - Biomet R&D connection
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=174053136

Sintx - Zimmer Personnel Connection
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=174053353

Dr Pezzotti member of Sintx scientific boards studies for Biomet (Not conmprehensive
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=174052660

Mr Bond, they have a saying in Chicago: 'Once is happenstance. Twice is coincidence. The third time it's enemy action'.


One is an incident, two is a coincidence, three's a pattern, and four is enough for a warrant



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You can see those debating my on this forum all utilize forms of disinformation techniques instead of directly addressing the various points made with evidence:
https://www.ethosdebate.com/lies-rhetoric-4-18-rules-disinformation/

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Silicon Nitride, a Close to Ideal Ceramic Material for Medical Application

examples of their medical applications that relate to spinal, orthopedic and dental implants, bone grafts and scaffolds, platforms for intelligent synthetic neural circuits, antibacterial and antiviral particles and coatings, optical biosensors, and nano-photonic waveguides for sophisticated medical diagnostic devices are all covered in the research reviewed herein. The examples provided convincingly show that silicon nitride is destined to become a leader to replace titanium and other entrenched biomaterials in many fields of medicine.


https://www.mdpi.com/2571-6131/4/2/16/htm

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Extra information on the status of a Si3n4 based hip implant:

Silicon nitride, silicon carbide and diamond-like carbon as non-oxide ceramics are considered to be the new generation of materials used in hip prosthetics, particularly in the manufacture of acetabular cups, due to their excellent biocompatibility, osteointegration, and tribological and mechanical properties, but all three materials need more study. However, silicon nitride is the nearest to commercialization, through businesses such as Amedica Corp. and SyntX Technologies


Im guessing the authors meant Sintx Technologies. Amedica being the companies former name before the name was sold to CTL.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10422432/

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Electromagnetic fields, metal implant corrosion, and dis-ease it causes


https://i.imgur.com/nLg7SXT.jpg

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=172932779

Could it be that there is a strategy to distract people away from looking at the basic data?
Is all this an exercise to create more and more forum verbiage to drown out any serious discussion of evidence?

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