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Mufaso

01/09/24 3:30 PM

#250318 RE: Mufaso #250317

Pure speculation on the new mystery non-glp obesity compound PFE is testing is that the MOA is similar to what Kallyope is targeting with K-757 and K-833. There are many well know Hormones having an impact on appetite and satiety. Kallyope has disclosed that they target cholecystokinin (CCK) and Peptide YY (PYY), but there are many other well know hormones that could be target including Leptin and/or Ghrelin. For those interested, here is a good article on "Hormonal Regulators of Appetite"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777281/
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DewDiligence

01/10/24 12:21 PM

#250325 RE: Mufaso #250317

The context of the excerpt you posted from PFE’s JPM webcast makes me pretty sure that the drug in question is oral.