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The Danish Dude

11/24/23 5:15 PM

#650431 RE: Baxers #650428

My God the rotten stench.
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dstock07734

11/24/23 7:13 PM

#650440 RE: Baxers #650428

I feel sorry for those professionals. They are supposed to be very smart. The publication will tarnish their reputation eventually and even bring stigma to their professional life. Well, Neil Armstrong went to Congress testifying against SpaceX. So you never know what those people are really thinking. I ever wonder if they went through all the presentations on DCVAX-L, the Nature preprint, even the whole package of the JAMA paper.
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notbrad

11/24/23 11:14 PM

#650453 RE: Baxers #650428

Further down in the 'Conflict of Interest' section of the paper it states the following:

"E.A.C. (E. Antonio Chiocca) is an advisor to Amacathera, Bionaut Labs, Genenta, Inc., Insightec, Inc., DNAtrix Inc., Seneca Therapeutics, Theravir. He has equity options in Bionaut Laboratories, DNAtrix, Immunomic Therapeutics, Seneca Therapeutics, and Ternalys Therapeutics. He is co-founder and on Board of Directors of Ternalys Therapeutics".

And guess what, these companies are all involved in developing treatments for GBM:

Genenta, Inc - GBM Phase 1/2 and other solid tumors
Insightec, Inc - GBM Phase 2
DNAtrix Inc - GBM Phase 2 and 3
Immunomic Therapeutics - GBM Phase 1
Ternalys Therapeutics - also involved in GBM research using microRNA.

And this guy is a Harvard Medical School-affiliated doctor !
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jon_k84

11/25/23 8:58 AM

#650480 RE: Baxers #650428

Also, scroll on down to the conflicts of interest:

Advisor to Novocure. At least this time they had the decency to disclose it. This article belongs in the trash-bin much less the editor's choice stack.

One thing none of these article are able to explain to me (and the simplicity of it is astounding) - if DC-Vax doesn't work, why are there a significant number of previous unheard of survival durations? 10+ years with GBM practically never happened before DCV. Anyone have a serious rebuttal to that?
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Baxers

11/25/23 3:50 PM

#650560 RE: Baxers #650428

Amazingly I just heard back from Dr Chiocca... on a Saturday no less (screenshot attached). Maybe he is feeling the heat having had more than a few people point out this schoolboy error!

It will be interesting to see whether the Journal retracts the paper based on this. I somewhat doubt it!