My best-educated hypothesis is that clearly, the DCVax-L trial is going to return a positive result on the primary end point
The nice thing about this PFS review also is that there is no crossover effect between the curves such as could occur with my prior overall survival analysis OS.
As I recall, the primary endpoint for the original trial prior to any changes was overall survival. Not PFS. A prior trial using only four antigens from IMUC was negative on PFS back and I think 2013 or 2014. so I don’t know why everybody is making such a big deal about the PFS when it wasn’t even the primary endpoint of the original study. They’re like saying it is when it wasn’t.
What total nonsense. Everybody here knows that PFS was always the primary. Who are you even trying to convince with this.?
And you are still diverting from the core issue. That is OS between the trial arms (233 vs 99). Flipper knows it is still key, that is why he is trying to convince people that data is good.