NorthWest Biotherapeutics Inc (NWBO)

[alphapuppy]

As I recall, the primary endpoint for the original trial prior to any changes was overall survival. Not PFS. A prior trial using only four antigens from IMUC was negative on PFS back and I think 2013 or 2014. so I don’t know why everybody is making such a big deal about the PFS when it wasn’t even the primary endpoint of the original study. They’re like saying it is when it wasn’t. The significance of pseudo progression cannot be overstated, especially in those early years when things could get coded as progression when they really weren’t, that’s why overall survival is so important overall survival is the gold standard. Just my two cents.