exwannabe,
The science is not completely hidden but was and still is very, very well protected. There are specific things in maturation and activation that are discussed in the patents but are almost never discussed in the general language about activation/maturation. There are specific end product cell characteristics with cytokine and chemokine production that are different than what other DCs produce because of this. This is all about creating DCs that have optimized signaling through activation that is different, maturity that is different and purity that is better that what others produce. Those little tweaks you speak of are very important. Some tweaks, like the amount of time and activators used to create mature DCs that produce certain levels of TNFalpha, IL 12 and other markers of proper activation are known about generally but not the actual exact time or the exact activators other than IL-2 and CSF-1 which is protected though described in the patents and are within the list of potential activators. So you see that the science actually does matter because the recipe matters and the recipe has a right to be protected to a certain extent. Do you know the exact O2 and CO2 levels for cell differentiation and maturation or exact process for creating strongly polarized down to non polar sites on receptors or ligands? It’s all in the tweaks and NWBO has been tweaking while the world was learning about twerking. Big difference; ). Care to tell me all about what NWBO knows about macrophages that makes their platform the one to try to compete against?; ). Best wishes.
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