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CrashOverride

07/04/23 9:06 PM

#606669 RE: HyGro #606668

Majority are behind Landmark Trial Results
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Dr Bala

07/04/23 9:50 PM

#606672 RE: HyGro #606668

This nonsensical post is totally deaf to the outstanding efficacy of the JAMA data, hence the confusion in the post. On the other hand, please post on the INDIGO stats and the low glioma competition which might create some interesting discussion.
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dstock07734

07/05/23 12:35 AM

#606694 RE: HyGro #606668

Plenty of neuro-oncologists


False. Just some neuro-oncologists who were afraid to disclose the conflict of interests. Do any of them know about DCVax-L better than Dr. Liau and Professor Ashkan? Do any of them know that three shots of DCVax-L can trigger long time anti-tumor immune response? Do any of them have GBM patients who received treatment from them and are still alive after five years?

Is FDA negative response the last hope that shorts expect to free them from the trap? For the longs, approval already happened. What is going to happen in reality is just a formality. We cast our eyes much farther into the future.

Have you read the story about Joels and Owain. Why did Professor Ashkan have the confidence that three shots are enough? Any idea about how long dendritic cells can live?

From the time the dendritic cells reach lymph nodes, they can live from a few days up to maximum one week. Three shots of DCVax-L are administered within 28 days. In Owain's case, several months (four months as I recall) after the treatment, which means the original dendritic cells loaded with tumor antigen were all gone, yet Owein's tumor was still shrinking. You do know what that means, don't you?