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Biowatch

12/16/22 9:52 AM

#244772 RE: DewDiligence #244768

Colon cancer markers in stool (Cologuard) presumably more highly concentrated than they would be in blood in the general circulation, as the former probably comes directly from bleeding polyps, and the latter is diluted by the total blood volume in the body.

As a guess…

Then again, Cologuard could be subject to sampling error, i.e., you didn’t swab the part/side that scraped across the suspect polyp.
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dewophile

12/16/22 10:31 AM

#244774 RE: DewDiligence #244768

it's still crap in a cup and a trip to UPS
I just think there will be some patients who are at the doctors office anyway who come clean and say they aren't bothering w colonoscopy or even cologuard (as easy as that is) who the doctor says ok then let's go to plan C - you are low risk but I'll throw in this blood screen along w the other tests you are getting anyway
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swampboots

12/16/22 11:04 AM

#244775 RE: DewDiligence #244768

Once a colonoscopy is sort of ok ( no more surgical cut and pokes for years ) a Cologuard may be suggested as best diagnostic tool for further near term investigation if blood tests later triggers another required validating look ( ulcers, sudden anemia, suspicious inflammations), in absence of any clearly acquired known disease.
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stocksrising

12/19/22 12:43 PM

#244792 RE: DewDiligence #244768

Coming from personal experience, after FDA approval and launch, I did my first Cologuard sample, came back negative.. fast forward to June 22’, it picked up DNA stool issues and had colonoscopy in November..10 polyps removed( not cancer) but doc has concerns and doing 2 Colonoscopy 1 Yr. from now!
Highly recommend to all to try both procedures, both may save your life!!
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Fred Kadiddlehopper

07/29/24 4:30 PM

#252723 RE: DewDiligence #244768

Mainz biomed seems to have the edge on all similar products but the stock is seriously underperforming.