News Focus
News Focus
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Dr Bala

12/10/22 2:25 PM

#547006 RE: exwannabe #547001

Silence tells nothing. Nonsensical implications here. The results revealed tell a great story. The data is king.
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HyGro

12/10/22 2:40 PM

#547020 RE: exwannabe #547001

Trials need to offer a rescue to assist in recruiting -- a patient getting an experimental treatment wants assurance they will have a rescue option if it fails.

From the trial protocol filed on clinicaltrials.gov:
"All patients will have the option to receive DCVax-L in a crossover arm upon documented disease progression. "

So DCVax-L was the only other option NWBO was offering other than leaving the trial.
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Hopeforthefuture3

12/10/22 3:03 PM

#547031 RE: exwannabe #547001

Ex, I don't exactly remember the details but in the presentation by Dr Liau (taken down a day later) she briefly spoke about those that did not crossover. I think she said most were too sick and either couldn't or chose not to cross. I do imagine a few were in the 5% that seem to do well on soc (just my opinion)
Hope the series of PRs start coming this week
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Lykiri

12/10/22 3:47 PM

#547054 RE: exwannabe #547001

We do not know how many of the 233 treatment arm "crossed".


Odd we have not heard this presented. Sometime silence tells a lot.


Ex,

JAMA

232 Patients received DCVax-L (treatment group)
120 Continued with DCVax-L on recurrence