Replies to post #547020 on NorthWest Biotherapeutics Inc (NWBO)

[SkyLimit2022]

Good point!

That’s why the pembrolizumab study is intriguing! This study uses no chemo, no radiation, and there is no mandatory crossover design. Crossover is not required because 100% of the placebo control group are receiving murcidencel.

https://clinicaltrials.gov/ct2/show/NCT04201873

[Dr Bala]

Wrong. From the JTM 2018 paper:

All patients were allowed to receive DCVax-L following
tumor progression/recurrence, as well as other approved
treatments per local practice.

From the JAMA results, best option would have been DCVax-L.