Replies to post #529380 on NorthWest Biotherapeutics Inc (NWBO)

[Goats'nCrows]

Mulholland dispatched this BS.

It was financial. Giving these posters an inch on these issues is detrimental to progress.

The question has been answered.

[skitahoe]

Please correct me if I'm wrong, I believe that when the trial resumed it was agreed that all patients would receive the DCVax-L. Essentially at that time the regulators abandoned the control group and PFS as the primary goal. It took years to formalize what went on here, but in the end everything is falling into place including the use of historical data rather than control groups.

I certainly don't know, but I believe that in the future few trials for fatal disease will be done with control groups, new trials will allow all patients to get the experimental products. I believe this will make getting into clinical trials more desirable and have less patients dropping out when they determine they're not getting the experimental drug. Have no doubt, some patients can get their personal physicians to run tests that can almost definitely say whether they're getting the experimental treatment, or not.

This change is not being brought about by NWBO alone, but our trial certainly is helping to move the regulators in that way.

Gary

[HyGro]

FDA lift the partial trial hold when the company announced they were not going to recruit anymore patients. The issues that precipitated the partial trial hold were still part of the trial data. We'll see if it adds the the rest of the issues with the trial. Normally trial holds are serious issues. FDA doesn't do them without substantial evidence of an issue.