Replies to post #354393 on Anavex Life Sciences Corp (AVXL)

[saxxie2]

Since the animal studies were clear, why not self administer blarcasemine from a supplier like this one?

https://aobious.com/aobious/sigma-receptors/12980-blarcamesine-ae-37-hcl.html

[end2war]

"We have other indications that we have not mentioned yet."

That comment by Missling is really a huge item (along with his mention of
a pain killer indication), that will not get much thought because it is so lacking in specifics.

But, IMO, it merits emphasis because I believe it means they have done animal studies that make them believe A2-73 and/or A3-71 demonstrates potential benefical clinical effects in other indications they did not want to mention yet.

I recall Missling saying he did not want to dilute attention to those other indications just yet. Guessing, epilepsy, ocular disorders, or even fighting viruses in the brain, as George keeps talking about, as among the possibilities not yet mentioned.

However, the point I would stress, is that AVXL's ligand drugs that cause S1R activation are looking, more and more, to be the basis for a successful platform which can benefically impact many rare diseases.

This statement by Missling offers more indirect evidence that S1R activation is really one of natures neuroprotective mechanisms, and we have only just begun to understand how much S1R activation can do...Slow, Stop, Reverse and Protect!

What more will it take for the market to understand where AVXL trial results are pointing? >>>>> Something BIG is coming...maybe in a few months.

Make sure you do your own research and DD, and never rely on posters. GLTY.

[RedShoulder]

Missling on the CC: "We have other indications that we have not mentioned yet."

Falconer: "Consequently, HSP may well be one of Missling's diseases "not mentioned yet." If it's not, it should on his ever-widening list. I'm eager to be a test subject in a clinical trial of blarcamesine for HSP. If I'm not stuck in the placebo arm, I'll be able to get rid of my walker and gait about with normal ease."

falconer, I'm pulling for you because it looks like it may treat your disease.

Falconer: "lack sufficient levels of gamma-aminobutyric acid, GABA. With that deficiency muscle-controlling nerves become hyperexcited and fire continuously. The attached muscles are continually contracted; are spastic."
-------------------------------
All the trials have helped the GABA regulation, so that looks very good for your condition. If they don't do a trial for HSP, I'm sure your Doc will be able prescribe it off label. Good luck falconer to getting HSP successfully treated.

[frrol]

Slow down. You're not a physician or biologist, and be wary of confirmation bias. It's not a magic bean.

There's a lot of pumping out there, and a lot of nonsense (both bullish and bearish). Hopefully no one is getting misled into excessive risk.

[XenaLives]

Is HSP a disease?

Or is a causative factor for multiple CNS?