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Re: falconer66a post# 354393

Wednesday, 03/16/2022 1:34:43 PM

Wednesday, March 16, 2022 1:34:43 PM

Post# of 458377

"We have other indications that we have not mentioned yet."



That comment by Missling is really a huge item (along with his mention of
a pain killer indication), that will not get much thought because it is so lacking in specifics.

But, IMO, it merits emphasis because I believe it means they have done animal studies that make them believe A2-73 and/or A3-71 demonstrates potential benefical clinical effects in other indications they did not want to mention yet.

I recall Missling saying he did not want to dilute attention to those other indications just yet. Guessing, epilepsy, ocular disorders, or even fighting viruses in the brain, as George keeps talking about, as among the possibilities not yet mentioned.

However, the point I would stress, is that AVXL's ligand drugs that cause S1R activation are looking, more and more, to be the basis for a successful platform which can benefically impact many rare diseases.

This statement by Missling offers more indirect evidence that S1R activation is really one of natures neuroprotective mechanisms, and we have only just begun to understand how much S1R activation can do...Slow, Stop, Reverse and Protect!

What more will it take for the market to understand where AVXL trial results are pointing? >>>>> Something BIG is coming...maybe in a few months.

Make sure you do your own research and DD, and never rely on posters. GLTY.
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