My interpretation of current premarket and the bad faith Feuerstein tweet is as a reflexive short attack, not unlike what we saw with the initial great PDD data. No one is selling this news on the merits (and no one sold on the PDD merits then).
We may see a delayed price reaction to AVXL material good news, again, until this manipulative attempt is once more overtaken by normal market forces. Analysts will now upgrade.
There is nothing wrong with an endpoint like this unless it is post-hoc and better than the original endpoint. Missling MUST explain this at 830 or else results are open to interpretation.
As with Feb ish, I have (for some time now) been leery of over analyzed data. Would that be a legit fear given your explanation?