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sukus

01/03/22 1:17 PM

#431593 RE: flipper44 #431590

So, if the results are good, then manufacturing is the only bottleneck.


Agreed.

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flipper44

01/03/22 1:18 PM

#431595 RE: flipper44 #431590

BTW, Advent Sawston was closed today in observance of the New Year holiday.
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iclight

01/03/22 1:20 PM

#431596 RE: flipper44 #431590

If the unblinded data was good, you would have known it by now.
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The Danish Dude

01/03/22 1:21 PM

#431600 RE: flipper44 #431590

Agree.

And instead of having released TLD early last year, NWBO has progressed either way with exactly the same stuff, as they should've anyway.

And then came the small feather regarding WHO CNS5, that glioblastomas will comprise only IDH-wildtype tumors.

2021 Top Story in Brain Cancer: The 2021 WHO Classification of Tumors of the Central Nervous System

https://www.practiceupdate.com/content/2021-top-story-in-brain-cancer-the-2021-who-classification-of-tumors-of-the-central-nervous-system/127380/31/12/3

Suddenly NWBO had time to do a small round-the-table event regarding that, peer reviewing the journal and small talking with statisticians, which probably have also had quite a nice impact also on primary endpoints, if I've listened carefully.
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Chiugray

01/03/22 1:57 PM

#431619 RE: flipper44 #431590

Worth repeating because people say "BLA" 3 times and get lost.

People tend to forget that NWBO and contractors have had 14 months in which to develop a BLA if they chose to do so. The blur/flaw in peoples’ brains is the faulty thinking that a publication and BLA can’t be worked on concurrently.