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falconer66a

10/28/21 6:02 PM

#334057 RE: raja48185 #334055

Thank you. Good idea. In the comments section I just posted this note:

Interestingly, the study showed that “activation” of the sigma-1 receptor protein resulted in increased production of amyloid beta. Looks like that particular protein in neurons is a culprit in Alzheimer’s disease.

However, another sigma-1 receptor activator, Anavex Life Science’s blarcamesine (Anavex 2-73), does just the opposite. Its activation of the protein causes the protein to take on or resume modulation or facilitation of a number of homeostatic processes in the neuron. With those, the neuron functions normally, Alzheimer’s symptoms abate (or are prevented).

Scrutinize the schematics on Anavex sigma-1 receptor activation here:
https://www.anavex.com/sigmaceptor-explained