Replies to post #325905 on Anavex Life Sciences Corp (AVXL)

[McMagyar]

That made some people sick..
It was a single dosing

Some could try 100 Mg a day/ 50mg twice

[frrol]

Good evidence now that most patients can be dosed adequately with 2-73, which is a risk factor for every experimental compound. I think we've got that established, for adults. Perhaps not for optimum effect. I'm not sure to what extent the dual dosing arms are for dose effect and for tolerability. I suspect we get better tolerability data and insight from the OLE's.

I think the drug tolerability risk is now low at this point.