The reason is patient variability. Your blood level of a drug is not going to be same as mine.
If I weigh 300 lbs and you weigh 150 lbs, for the same dose our levels are vastly different.
Hence the argument that the generic has less drug than brand does not hold water.
These differences and “hypothetical “ lower purity are not based in science.
If there is evidence that generics are delivering 2 g instead of 4 g and FDA is clueless about it , then the discussion is different. Otherwise, minor differences (within FDA regulation) do not matter, no matter what we say.
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