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flipper44

01/05/21 3:22 PM

#345052 RE: jammyjames #345039

No, but when you are conducting a seminal trial, a blinded trial prevents the dangerous benefits of excessive manipulative (real-time) censoring. Novocure chose an unblinded trial and then excessively censored and also gave unhinged long term survival predictions. Cherry picking dream. They exponentially enhanced their cherry picking in their percent compliance study.

Regarding yours second point:


They simply don't have long enough follow up to say anything meaningful about long term survival and it was immoral of them to quote that 5-year KM stat.



Uh, that’s what I mean by unreasonably forecasting long term survival stats, but it’s not just five year km analysis, it’s also four year km analysis they don’t have enough long term follow up. You simply can’t handle words like unreasonably “extrapolate” or “forecast.” I get it. I disagree with that detail.

You also want to limit the damage to Novocure’s five year survival stats, when their trial is flawed across the board.

Why do you think Dr. Liau would state that her, and many of her colleagues do not believe Optune works?
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X Master

01/05/21 4:46 PM

#345101 RE: jammyjames #345039

Jammy, did you mean to say, and it “is” immoral of them to quote that 5-year KM stat. I would agree and they should be prohibited from quoting any stats beyond the 2 years (when they stopped the data).