Replies to post #243662 on Anavex Life Sciences Corp (AVXL)

[anders2211]

I haven't checked individual sites but Spain is at a standstill in regards to Alzheimer's studies (from Cyosol on NTRP board).

PDD is the same demographic.

It would not surprise me that there is a delay for the Alzheimer's enrolment. However, given where they are in the PDD I disagree that the 14 weeks PDD update will be delayed.

Across the board, clinic leaders said they are staying in contact with their participants and carers through remote methods such as phone calls, video conferences, internet contacts, even postcards. Researchers can continue to collect some clinical and cognitive data through these means. Meanwhile, they are using the down time to analyze data and prepare manuscripts.

There is a huge difference between enrolment and the continuation of ongoing clinical trials. In other words, one can not just stop the administrating of the drugs the patient is on. Of course, I don't need to tell you that.

As I have said before Spanish authorities have specifically stated that doctors/clinic visits will and must continue. I have experienced Spanish health care first hand if they would stop medical trials they would specifically communicate this on websites.

[frrol]

The hope is that we were far enough along with the PDD trial to have robust reportable, if not submittable, data. If patients and PIs perceive therapeutic effect, I wonder how much pressure they can bring to bear on the trial clinics to continue with treatment under some kind of accommodation protocol (remote visit, tele-assessment, interim cancel, etc.) In-patient facilities (hospitals) will have their hands full right now, but not out-patient.

We'll see.

[LakeshoreLeo1953]

Doc...Procedural inquiry:

What is the effect on the trial IF fatalities
from CV19 include previous enrollees?

Continuation of OLE and completion of the trial
are affected as much by the healthcare specialists
possible infection as access to facilities...it seems to me.