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georgejjl

03/27/20 10:16 PM

#243589 RE: georgejjl #243581

The coronavirus protein Nsp6 interacted with the Sigma 1 receptor, which is a target of chloroquine.




Like chloroquine, Anavex 2-73 binds the sigma-1 receptor in the high nanomolar range.

Good luck and GOD bless,
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Amatuer17

03/28/20 8:20 AM

#243611 RE: georgejjl #243581

You can try to connect everything to sigma 1 receptor but as long as company is not saying anything about it all talks are vapor ware.

Company is a CNS disease company and sticking to it.

Many BP have announced pausing trials and that is likely to impact Rett and ALZ enrollments. Many hospitals have stopped the trial intake or follow up visits to avoid contacts. This is impacting large number of current trials.

AVXL best bet is PDD as enrollment was completed in Jan. However Spain is badly impacted and not sure how it will impacted 14 week reading for last batch patients. If that cannot happen the trial results will be delayed.