Funnygi2, I think that’s as reasonable a guess as any. I think Europe pop is actually 750M or so, double US. However, US statin-taking population is roughly 40M, or around 15% of pop. A 2013 CEDC report put European statin use at around 9% of pop, but that could be around 60M. And yes, V cost will be significantly lower in Europe, just don’t know how much lower. As for BO if your $50B is the right gross revenue, maybe it pushes to $25B? Anybody’s guess,