Replies to post #238514 on NorthWest Biotherapeutics Inc (NWBO)

[sukus]

Flipper is back! Nice to have you back Sire! :-)

[exwannabe]

Idiocy. The FDA and Novocure people responsible for saying expected 13% alive at five years in their phase three Optune EF-14 final analysis treatment group should be sent packing. Only 12% (number = 57 out of 466) were alive at two years after the last patient’s enrollment. Only 3.4% ( number=16 of 466) had made it to five years by two years after last enrollment and most of those 16 likely were part of the 57 still alive. It’s downright criminal.

Yes, K/M curves are idiocy?

Maybe you should let the FDA, EMA, NICE, biostatisticians, clincal researchers and LL and the 65 other authors all know that.

As far as your flawed analysis. The 57 alive at EOS does not include LTFUs. Because of the design, the trial had a significant number of LTFUs past 2 years on trial. The purpose of K/M is to handle survival curves with missing data. That is what is has done.

There is a reason survival stats are presented as K/M and not all this hand waiving about "actual" numbers and alive at so long past end of enrollment. The reason is called math.

Was the DCVax-L paper "criminal" when it asserted a 12% OS at 88 months when only 1 or 2 patients lived that long? That was a K/M with far more missing data than the Optune 5 year number.

[Basin Street Blues]

Flipper,
Take a look at this chart it shows Green for insider buys and Red for insider sells ..

So ordinarily if you were a HF who punted around in this stuff you`d look for two companies in the same sector as you`d get automatic protection from macro movements, so you`d sell NVCR and buy NWBO but you wouldn't because
if you even suggested to your compliance & risk department to buy an
OTC penny stock with zero transparency and a record for using shareholders like a U bend you'd get an immediate `NO` and more importantly your credibility as a PM would be in tatters.

Whatever the real driver behind radio silence from LP by definition it hasn't worked we are at 21 cents and still diluting .

So should anyone at NWBO tells you the silence plan is to `Scupper Mr Shorty ` at best they are being disingenuous and worst lying manipulators.