I believe Anavex Australia began advertising for patients already in July 2018 There has been a good amount of prior publicity around the A2-73 P2a trial in Australia, so it would be fair to assume a flying start to recruitment.
As of December 2018 75% representing 9 of 12 trial sites were active.
Let's say that each trial centre recruits just 5 patients per month and that two new sites are activated per month, which would give us 9 by mid December.
Sept: 2 centres * 5 patients each = 10 Oct: 4 centres * 5 patients each = 20 Nov: 6 centres * 5 patients each = 30 Dec: 9 centres * 5 patients each = 45 Total recruitment by end Dec = 105 At same linear rate: Jan: 11 centres * 5 patients each = 55 Feb: 12 centres * 5 patients each = 60 Mar: 12 centres * 5 patients each = 60 Apr: 12 centres * 5 patients each = 60 May: 12 centres * 5 patients each = 60 Jun: 12 centres * 5 patients each = 50 End June 2019 fully recruited = 450 patients Dosing 48 weeks -> topline data mid 2020