Replies to post #176024 on Anavex Life Sciences Corp (AVXL)

[XenaLives]

Is there any reason to put all the marbles in this argument and ignore the M1 qualities of the drug?

Is there any reason/evidence to expect that 2-73 agonism is better??? (along with the issue of relative affinities can prevent receptor access).

[Steady_T]

There is reason/evidence for belief that 2-73 is better.

The issue is that it is not conclusive. I classify it as suggestive due to the small numbers involved and the lack of more complete data to allow for independent analysis.

P2B/P3 will give a more definitive answer to the question I hope.

I understand all of your criticisms of the data and the possible ways it could be misrepresented or cherry picked. That is why I say the evidence is not conclusive but suggestive.

Still I see the balance of available information as being positive for 2-73.

YMMV