Federal jurisdiction of the FDA stems from the necessity of interstate transport of the drug to conduct human trials therefore as a practical matter needs an approved IND. However where there is a will there is a way especially in high stakes situations. BIIB of course could run any type of non-human CT for any indication and not even violate the MTA as they could easily attribute it to advancing the MS indication. One would assume BIIB has been testing A2-73 in everything from arrhythmia to Zosters.
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