Replies to post #149275 on Anavex Life Sciences Corp (AVXL)

[bas2020]

Isn't the Rett trial going to be mostly from patients' homes? Can you elaborate?

[McMagyar]

Take it one step farther..

The time between trial start and fully enrolled.. will not be long either..
On a 12 week study...


Short away shorty mc short short..
Your time to pay the band arrives soon enough. Hope the band of distorters enjoyed their dance on the floor of maladies...

[LakeshoreLeo1953]

Are they interviewing CRO(s)?
That would REQUIRE protocols for legit bid.

OR

Is the Company seeing what CRO(s) may be interested
in an as yet non specific trial?

Parsing the information from this Company continues to
be an issue. Then again, I guess everyone is correct no
matter how they interpret the "News".

[Amatuer17]

In most cases, company also needs to specify primary site in the IND application. The primary hospital site needs to agree to the trial and controls - all those details need to be included in the IND / protocol submission.

[Bourbon_on_my_cornflakes]

Great work Hapit.
Useful and positive info that will take real work to spin negatively.

Fact is AVXL is methodically proceeding on multiple fronts to starting trials.

TRUST THE PLAN

[plexrec]

hapit--"I had a long conversation with Clint today"--good stuff---thanks for your efforts !!!

[hokieal]

Found an interesting article from last year on some general observations for study start up delays. Based on the part I quoted below, it is a good sign if we are in the site visit portion because it means we have completed (or come close) all of the work leading up to this stage. Feels like we are getting close now.

Accelerating Study Start-Up: The Key to Avoiding Trial Delays

A study conducted by the Tufts Center for the Study of Drug Development determined that it takes eight months, on average, to move from pre-visit through to site initiation,1 out of which nearly six to eight weeks on an average are for sending feasibility questionnaires, having them completed, and receiving responses.2

Quite often, the finalized site selection itself eventually becomes a rushed process, whereby hundreds of investigators/sites across the globe are selected over a short span in an attempt to hasten trial start-up. As a result, poor selection of trial sites becomes a problem during trial conduct, and reportedly increases the cost of clinical trials by at least 20%.